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Five Best Alternating Pressure Mattresses for 2024

Five Best Alternating Pressure Mattresses for 2024
HPFY Staff Writer

Air mattresses or airbeds are the new age sleep comforters that not only give you a comfortable sleep but also help in combating many health problems that are caused or aggravated by the wrong sleeping posture. They improve the quality of life of people who suffer from back pain, sores, or any of these kinds of health problems. The ability to adjust the firmness and shape of a mattress to accommodate different body shapes, sizes, and weights, can be a major factor in the healing process. Moreover, air mattresses manufactured without the use of materials that may release VOCs or other toxic compounds from the manufacturing process can exacerbate allergies in children or other sensitive individuals. Here comes the technology of alternating pressure relief mattresses.

What are Pressure Sores?

Sustained pressure on the skin of a specific part of the body can result in skin and tissue damage. This damage is referred to as pressure sores. The constant pressure on that part of the body makes it vulnerable, wearing the skin down, and exposing the vulnerable part of the skin to external elements. Pressure sores are usually caused by sustained sitting or sustained sleeping. There are four degrees of pressure sores that usually increase by continuous sitting or sleeping in one position.

  • Degree 1 – Reddening of the skin
  • Degree 2 – Superficial blister-like wound
  • Degree 3 – All layers of skin damaged, along with tissue under the skin
  • Degree 4 – Skin and underlying tissue extensively damaged together with bone, muscle, tendons, or joints.

What is Alternating Pressure Therapy?

Alternating pressure therapy uses a kind of pressure redistribution that stimulates and regulates blood flow to the skin. The alternating pressure therapy is defined in cycle times. The lesser the time between each cycle, the more the amount of blood is allowed to reach the skin to relieve painful pressure points which then heals the bedsores. Some of the best alternating-pressure mattress systems offer adjustable cycle times.

What are Alternating Pressure Mattresses?

Alternating pressure mattress systems offer different and unique benefits. One of the primary reasons that one uses these pressure mattresses is to prevent or treat skin breakdown. Alternating Pressure Systems alternate inflation and deflation of air cells (bladders) to constantly change pressure points and promote circulation. Cycle time (head-foot) is about 10 minutes or programmable on some types of devices. These mattresses have bladders positioned laterally or length-wise which slowly deflate and inflate. This keeps the pressure alternating throughout the body.

Five Best Alternating Pressure Mattresses

1. Invacare MicroAIR MA500 Alternating Pressure Low Air Loss Mattress System

Invacare MicroAir MA500 Alternating Pressure Low Air Loss Mattress System is one of the best alternating pressure mattresses. It is lightweight and easy to use and aids in the Prevention and Treatment of Pressure Injuries. It has Cell in cell design which helps to prevent bottoming out in the event of a power failure. This gives ultimate patient comfort and relief.

Invacare MicroAir MA500 Highlights

  • 10 minute cycle time
  • Cell-in-cell design helps prevent bottoming out in the event of a power failure
  • The streamlined pump design is lightweight and unobtrusive
  • Audio and visual alarms warn the resident during a power outage


  • 2-in-1 alternating pressure cycles help ensure protection for residents with low to medium risk
  • Natural heel slope is designed to decrease pressure in resident’s vulnerable heel area
  • Soft nylon urethane-backed cells are designed to provide easy cleaning and help minimize the proliferation of bacterial growth
  • Highly vapor permeable and oversized pliable quilted nylon top cover is designed to provide low shear, friction, and moisture protection
  • 8 adjustable comfort settings depending on the resident’s therapy requirement
  • Audio and visual alarms warn the resident during a power outage
  • The streamlined pump design is lightweight and unobtrusive.

2. Medline Supra DPS Low Air-Loss Therapy Mattress 

It is designed to relieve pressure from the pressure points while a person is receiving nursing care at home or in a hospital. With its alternating pressure, static float, auto firm, and seat inflation function, the Supra DPS Mattress is one of the most commonly bought mattress systems. The low air-loss cells control moisture and prevent bottoming out during a power failure.

Product Features

  • Reliable
  • Easy to clean
  • Durable
  • Safe for people with latex allergies
  • Has an anti-shear stretch cover
  • Waterproof
  • Weight capacity: 400lb

Medline Supra DPS Low Air-Loss Therapy Mattress


3. Prius Healthcare Enhance DX Mattress System

Prius Healthcare Enhance DX Mattress System is a pressure relief mattress with 18 eight-inch air cells to help maintain a continuous circulation of dry airflow for patients who are at low to medium risk of developing pressure ulcers according to the use of sound clinical judgment. Enhance DX can also be used for patients who have an existing stage 1, 2, and 3 pressure ulcer. This mattress system provides constant low pressure by redistributing the patient’s pressure over a greater area than a standard mattress.

Reason to Choose Prius Enhance DX Mattress

  • Nylon woven fabric with PU coating finish
  • Cable management keeps electrical cables off the floor
  • A low slip base cover keeps the mattress in place
  • CPR quick-release system deflates the system within 20 seconds
  • The slimline pump design is unobstructed


  • The Enhance DX employs 8" air bladders with the cell-in-cell design (4.5" of therapy, 3.5" of static air), to provide therapeutic alternating pressure and also allow the mattress to stay inflated in a power outage
  • Durable woven polyester bottom cover with PVC lining for infection control
  • The Enhance DX replacement mattress can accommodate patient weights up to 500 lbs
  • Low friction, low shear cover
  • Easy to clean and maintain
  • 2 in 1 alternation
  • Pressure mapping

4. Drive Med-Aire Plus Bariatric Alternating Pressure and Low Air Loss Mattress Replacement System

As one of the best alternating pressure mattresses, Drive Med-Aire Plus Bariatric Alternating Pressure and Low Air Loss Mattress Replacement System is designed to provide alternating pressure to optimize pressure redistribution for patients with up to Stage IV pressure ulcers. The Cell-on-Cell design of 10-inch deep air cells prevents bottoming out and also provides up to 24 hours of power outage protection. The mattress is ideal for use in nursing homes, hospitals, and home use.

Product Features

  • Designed to prevent, treat and heal all stages of pressure ulcers in the home or long-term care setting
  • The digital control unit offers 4 cycle times and adjustable comfort weight settings for optimal immersion and patient satisfaction
  • 3 diagnostic audio and visual alarms alert for issues with air pressure, the system, or power
  • The system includes 20 individual air cells to maximize immersion and envelopment with a pillow feature for head stability & comfort
  • Cell-on-cell designed air cells prevent "bottoming out" and provide up to 24 hours of power outage protection
  • 10" deep air cells are easily removed with quick disconnects for convenient servicing
  • CPR valve allows for rapid deflation

5. Meridian Ultra Care Xtra Bariatric Alternating Pressure Mattress

Meridian Ultra Care Xtra Bariatric Alternating Pressure Mattress has a Stay-Flate cell-on-cell air bladder construction to provide a full ten inches of therapeutic support with bottom-out protection in the event of a power failure. In addition to the Alternating Pressure mode, the Static mode provides a firm surface when needed. Regardless of the operating mode, the mattress maintains the low air loss benefit.

Features of Meridian Ultra Care Xtra Pressure Mattress

  • 16 liter-per-minute pump in an easy-to-use design
  • Two modes of therapy - static or alternating
  • The pillow function maintains the air cells at the head for patient comfort
  • Twenty rows of 10" alternating pressure air cells, nine with laser holes to keep the patient cool and speed recovery
  • Air cells made with nylon/polyurethane for increased durability and reliability
  • Quick disconnect cells for easy cell replacement
  • CPR quickly deflates at the head of the mattress
  • Quilted nylon zipper cover is low shear, fluid-resistant, and vapor permeable

What are its Advantages?

  • Cells are easily cleaned
  • The zipper cover is quilted vapor-permeable nylon
  • Water-resistant
  • Easy cleaning
  • Quick disconnect cells allow any area of the mattress to deflate and be zero pressure without affecting alternating benefits
  • Dual compressor for increased patient comfort and weight capacity (100 lbs.) 10, 15, or 20-minute cycle times
  • Five comfort settings for easy pressure adjustment
  • Automatic reset from static to alternating after 45 minutes
  • Quick Inflate Pump reduces inflation time dramatically

Where to buy the Best Alternating Pressure Mattress online?

At Health Products For You, we have an extensive range of best alternating pressure mattresses that provide exceptional comfort while sleeping, great protection from pressure sores, and comfortable sleeping for elongated periods of time. 

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Disclaimer: All content found on our website, including images, videos, infographics and text were created solely for informational purposes. Our content should never be used for the purpose of diagnosis or treatment of any medical conditions. Content shared on our websites is not meant to be used as a substitute for advice from a certified medical professional. Reliance on the information provided on our website as a basis for patient treatment is solely at your own risk. We urge all our customers to always consult a physician or a certified medical professional before trying or using a new medical product.


HPFY HPFY Staff Writer

HPFY Staff Writer

HPFY Staff Writers are product experts with years of experience in medical supplies and equipment retail. They specialize in understanding the typical usage of our products, the differentiation between brands and have insights on product popularity and features. Each article ...

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