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No, this is common problem that can easily be solved. The most common problem is a kink in the air hose. Open the cover and check the air tubes under the cells that run along the inside of the mattress. Massage the hose with your fingers to make sure there is not a kink in the hose. Apply some weight to the mattress and allow some time for the mattresses pump to reinflate all the sections.
Yes you can use a standard hand or powered pump by connecting it to the CPR tag. Removing the CPR tag will open a direct valve that allows air to flow quickly into the mattress at a faster pace.
If there is bottoming-out that means the pressure setting is inadequate (or too low) for the patient. Bottoming-out can be checked by sliding your hand between the deflated air cell and directly under the patient. Patient should be able to feel the minimal contact. If there is an incident of bottoming-out, simply adjust the pressure range a little higher.
Wipe the pump with a damp cloth and a mild detergent and keep it away from dust. Clean the mattress cover and air cells by using a gentle laundry detergent allowing the unit to air dry.