Online since 2002 |   866-316-0162

Articles and News

Understanding Wound Inflammation

Understanding Wound Inflammation
Kevin Cleary

The wound healing process is generally understood to be a three-step process: inflammation, regeneration (also known as proliferation), and maturation. Wound healing is actually a complex series of events that involves cellular activity and the release of biological substances such as enzymes, carbohydrates, growth factors, and proteins. Each step in the process is there to support the next step in order to have proper wound recovery. Much like building a house and starting with a strong foundation, the inflammation stage of wound healing is the foundation for a successful recovery.

What is the Importance of Wound Inflammation?

In order to have a wound heal properly, the inflammatory stage plays a crucial part in the overall healing process. As an article for written by Mark Collier points out, the function of the inflammation stage is to neutralize and destroy any toxins at the site of injury and to restore tissue homeostasis. It is also characterized by heat and redness, pain and swelling accompanied by a raised temperature/fever. A person’s overall health and severity of the wound will have an impact on the effect of the inflammatory stage. Below is a simplistic view of the inflammatory stage of healing.

Importance of Wound Inflammation

It is at the moment of injury or trauma that our bodies leap into action almost immediately. For those that accept inflammation as the first phase of wound healing, hemostasis (the process in which bleeding is stopped) is included in the process. While this is the most widely accepted concept, there are those that believe hemostasis by itself is the first stage of healing. Once bleeding has stopped the use of wound cleansing products can help the wound bed area stay free of foreign debris and bacteria. Something as simple as BD Alcohol Swabs contain isopropyl alcohol for anti-bacterial protection or the Medline Curad Triple Antibiotic Ointment (contains bacitracin zinc, neomycin sulfate, and polymyxin B sulfate) can help prevent infection in minor wounds. Iodine wipes can be used for antiseptic skin preparation, so products such as the Dynarex Povidone Iodine Prep Pad or the Medline Povidone Iodine Swab Sticks are good options. Caution should be taken when using iodine since it can stain both skin and clothing, but in order to remove any iodine stains Nice Pak PDI Io-Gone Iodine Remover Pad should be used.


What are the Characteristics of Inflammation?

As soon as we injure ourselves our body’s invisible little biological army goes to work helping us down the path to recovery. Since the first step in recovering from any wound is widely considered the inflammatory phase, understanding these characteristics can help us determine if the basis for wound healing is progressing properly. According to, this process begins at the moment of injury and can last 2-5 days it’s at this time that hemostasis occurs via vasoconstriction, platelet aggregation, and thromboplastin makes blood clot to halt bleeding. It’s after this hemostasis that blood vessels dilate to allow other essential cells (antibodies, enzymes, nutrients, etc.) to reach the wounded area. As points out this is when there is a rise in exudate levels so it’s important to check the surrounding skin for maceration. The use of absorbent dressing such as Alginate Dressings and Hydrocolloid Dressings can help absorb wound exudate and help maintain a moist healing environment. For light to medium exudating wounds, hydrocolloid dressing products such as the Hydrocol II Hydrocolloid Dressing or the Systagenix Nu-Derm Bordered Hydrocolloid Wound Dressing can fit the bill. For heavier exudating wounds the use of alginate dressings such as the Sorbsan Topical Calcium Alginate Wound Dressing or the 3M Tegaderm High Gelling Alginate Dressing can absorb large quantities of exudate while maintaining a moist healing environment. Another dressing type that can be used is the Foam Dressing. These are highly absorbent and can be left untouched for 3-4 days. The Mepilex BorderSystagenix Tielle Hydropolymer Adhesive Dressing, and Medline Optifoam Thin Adhesive Foam Dressing are good options. The telltale signs of this point in the healing process are, among others, heat, pain, and functional disturbance.


How You Can Help the Process of Healing?

While our bodies are major players in the inflammation stage, we can help our natural healing process by helping to maintain a healthy healing environment. Once the bleeding process has stopped, keeping the site clean and free from bacteria can go a long way. Remember, a clean wound is a happy wound and will heal faster!!


Disclaimer: All content found on our website, including images, videos, infographics and text were created solely for informational purposes. Our content should never be used for the purpose of diagnosis or treatment of any medical conditions. Content shared on our websites is not meant to be used as a substitute for advice from a certified medical professional. Reliance on the information provided on our website as a basis for patient treatment is solely at your own risk. We urge all our customers to always consult a physician or a certified medical professional before trying or using a new medical product.


HPFY Kevin Cleary

Kevin Cleary

Kevin Cleary has been a Health Products For You contributor for many years and has a degree in marketing. His health and wellness journey has a very personal meaning and has guided him in his content writing for HPFY.

In 2006, ...

Read More

Trending Articles

What Everyone Should Know About Resistance Band Colors

Kevin Cleary

Resistance exercise bands come in a number of colors and it’s not just for decoration. Many people use these bands however, they do not have the knowledge of the colors and the purpose with which they are designed.

5 Facts about Syringes You Wish You Knew Before

Kevin Cleary

A syringe is a pump consisting of a snugly fit piston(or plunger) within a calibrated glass or plastic cylinder called a barrel.The syringe is equipped with a hypodermic needle, nozzle, or tubing that helps direct the flow of medication.


Kevin Cleary

Breathing disorders, such as COPD or asthma, can be a major detriment when it comes to quality-of-life issues.Treating these breathing ailments with medications is the main course of treatment.Being able to deliver aerosol medication directly into the lungs in an expedited fashion is the best way to manage these lung disorders. The use of a nebulizer for aerosol medications allows for the efficient and easy delivery of these medications.


Kevin Cleary

An enema is used for many reasons.Just as there are many reasons, there are different types of enemas, each of which contains different ingredients and works differently in the body. While some may choose an enema to soften stool or for routine colon cleansing, the reason for using an enema may have more of a medical necessity.


Taikhum Sadiq

Cervical traction is a technique applied to the cervical region of the body to help alleviate neck pain, discomfort, and other physical conditions related to the cervical region.Cervical traction works by stressing the neck, pulling, and pushing, thus reducing the pressure on the spine, the neck, and the upper torso.Excessive stress on the neck, spine, and upper region, due to a wide range of conditions or injuries can cause severe pain and can lead to other complications.Cervical traction devices help alleviates these conditions thus offering overall body rehabilitation and treatment options.