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The 10 Best Antifungal Creams in 2023

The 10 Best Antifungal Creams in 2023
HPFY Staff Writer

10 Best Cream for Fungal Infections

  1. Medline Remedy Phytoplex Antifungal Ointment
  2. Coloplast Baza Moisture Barrier Antifungal Cream
  3. Dynarex Antifungal One Percent Clotrimazole USP Cream
  4. Medline Soothe and Cool INZO Antifungal Cream
  5. Dermarite Periguard Skin Protectant Antimicrobial Ointment
  6. Coloplast Critic Aid Clear AF Antifungal Cream
  7. McKesson Antifungal 2% Strength Cream
  8. Smith & Nephew Secura Dimethicone Skin Protectant Cream
  9. Thera Antifungal Strength Cream
  10. Antifungal Lotrimin Strength Cream

Our skin is our largest organ and protects us from a plethora of germs and bacteria. It regulates body temperature, preserves water, absorbs sweat, and helps create vitamin D from sun exposure. However, sometimes bacterial and fungal growth can lead to skin infections, causing irritation, rashes, swelling, inflammation, and discomfort.

An antifungal cream treats skin infections caused by microscopic single-celled organisms called fungi that may live on human skin. Fungi can cause allergies, rashes, and even acute skin infections. These fungal infections are often treated with antifungal ointments and creams.

What is an antifungal cream? 

Antifungal creams treat fungal infections of the skin, hair, and nails and are available over the counter or by prescription. Antifungal medicines come in several forms, including creams, lotions, and sprays.

When to use an anti-fungal cream

Over-the-counter antifungal cream helps treat many types of fungal infections, including:

  • Ringworm 
  • Jock itch 
  • Athlete’s foot 
  • Tinea versicolor 
  • Yeast infections 
  • Nail infections

Mild fungal skin infections are easily treatable with strong antifungal creams and ointments. However, for untreatable fungus infections, it is best to consult a dermatologist to assess and offer treatment options.

How does an antifungal cream work? 

Creams for fungal infection work by hindering the growth of the fungus or killing it altogether and repairing damaged cell walls.

Typically, topical fungal infection creams consist of various ingredients effective in treating fungus infections, such as: -  

  • clotrimazole 
  • amorolfine 
  • econazole 
  • ketoconazole 
  • miconazole 
  • terbinafine 
  • tioconazole 

Antifungal cream for the skin is often mixed with other topical creams when two skin problems are addressed together. 

Best Antifungal Creams For Itchy Or Irritated Skin

Formulated with phytoalexin and other botanicals to help relieve itching, scaling, cracking, burning, soreness, redness, irritation, and discomfort associated with the most common superficial fungal infections of the skin. It creates an invisible shield that allows easy inspection. Moreover, Medline topical antifungal cream is also ideal for children over two years to geriatrics.

Benefits of using Remedy Phytoplex Cream for Fungal Treatment

  • Miconazole nitrate 2.0% in a petrolatum base formula softens skin.
  • Helps relieve cracked, scaly, itchy, and inflamed skin.
  • This ointment is ideal for:
    • Tinea cruris - jock itch
    • Tinea corporis - ringworm
    • Tinea faciei - facial fungal infection
    • Tinea manuum - a fungal infection of the hands
    • Tinea pedis - athlete's foot
Medline Remedy Phytoplex Antifungal Ointment


Inhibits fungal growth and works great on diaper rash, ringworm and athlete's foot by locking out moisture and allowing the infection to heal without irritating the skin. Coloplast Baza is the best antifungal cream for diaper rash that offers a soothing shield against urine and feces and relieves diaper dermatitis. Additionally, zinc oxide treats burning, itching and other painful symptoms of skin infections.

Benefits of using Coloplast Baza Cream

  • Coloplast diaper cream relieves fungus infection and diaper dermatitis.   
  • Provides a moisture barrier against feces, urine, and odor.  
  • Coloplast Baza is ideal for the treatment of perineal skin irritation. 
  • The miconazole nitrate cream wicks moisture away and prevents the growth of infection-causing fungus. 
  • Eliminates itching, redness, and burning and speeds healing.
Coloplast Baza Moisture Barrier Antifungal Cream


Formulated with one percent clotrimazole, this cream works great for infections like athlete's foot, jock itch, and ringworm. Dynarex jock itch cream treats superficial skin infections caused by yeast and soothes itching, cracked, scaly, irritated skin.

Features of Dynarex Clotrimazole Antifungal Cream

  • The long-lasting non-greasy formula
  • Helps relieve pain, discomfort, and irritation
  • Treats athlete's foot, jock itch, and vaginal yeast infections.
  • Suitable for long-term care facilities and first aid kits
Dynarex Antifungal One Percent Clotrimazole USP Cream


Effectively treats athlete's foot, jock itch, ringworm, and Candida albicans, this lightly scented ointment is formulated with 2% miconazole, known for its antifungal properties. This cream provides moisture barrier protection to the affected area and protects the skin from infections caused by incontinence and ostomy.

Benefits of Medline Soothe and Cool Cream

  • The clear formula for easy monitoring of the affected area.
  • Formulated with Cetyl Dimethicone and Zinc Oxide
  • Ideal to use around ostomy sites or peri-wound skin
  • Effective on dry skin.
Medline Soothe and Cool INZO Antifungal Cream


Versatile and effective, this topical ointment promotes healing while protecting skin. Formulated with a blend of ingredients, including zinc oxide and dimethicone, which work together to create a barrier that shields the skin from moisture, irritants, and harmful bacteria. Helps to prevent and treat diaper rash, chafing, and skin breakdown caused by prolonged exposure to moisture. Also grat for minor cuts, burns, and skin irritations.

Benefits of Periguard Skin Protectant Ointment

  • Fragrance-Free skin protectant ointment
  • Treats skin irritations associated with incontinence
  • Petroleum-based skin protective cream
  • Non-greasy
  • Washes off easily
Dermarite Periguard Ointment


Highly recommended as an effective bedsore treatment, this easy-to-apply fungal infection cream heals skin and pressure ulcers by creating a barrier against moisture.

Benefits of Critic Aid Clear AF Antifungal Moisture Barrier

  • R Qelieves perineal skin irritation.
  • Provides effective treatment of jock itch.
  • Minimizes the discomfort of diaper rash.
Coloplast Critic Aid Clear AF Antifungal Moisture Barrier


Formulated with 2% miconazole nitrate to relieve jock itch, ringworm, and athlete's foot, this cream minimizes itching, cracking, and scaly skin caused by fungus infection.

The McKesson Antifungal Foot Cream Features

  • Latex-free
  • Reduces discomfort
  • Relieves redness and burning
McKesson Antifungal 2% Strength Cream


Considered one of the best antifungal creams to treat toenail fungal infections and a great optional treatment to pills, surgery or laser therapy.

Features of Smith & Nephew Secura Dimethicone Skin Protectant Cream

  • Effectively treats toenail infections by controlling the growth of fungi
  • Protects skin.
  • Relieves irritation.
Smith & Nephew Secura Dimethicone Skin Protectant Cream


Formulated with 2% Miconazole Nitrate to helps fight most superficial fungal skin irritations and yeast infections. This moisturizing cream relieves itchy, cracked, scaly, burning, red, skin.


Benefits of Thera Antifungal Strength Cream

  • Helps protect against excess moisture in skin folds and inflamed areas.
  • Moisturizes the skin where incontinence or wound drainage is an issue
  • Recommended for skin folds, feet.
  • Latex-free
Thera Antifungal Strength Cream


Provides soothing relief to the infected between the toes and the bottom and sides of your feet. The smooth consistency helps applies easily on affected areas and is highly effective in treating infections such as athletes' foot and ringworm.

Benefits of Lotrimin Athlete’s Foot Antifungal Cream

  • Clinically proven to cure athlete's foot and control fungus that causes foot infections.
  • Soothing relief to itchy, infected skin.
  • Heals cracked, diabetic feet.
  • Use Lotrimin fungal treatment cream for ringworm daily for four weeks. Similarly, for jock itch, use the cream daily for 2 weeks.
Antifungal Lotrimin Strength Cream



Where can I buy Best Antifungal Cream Over The Counter?

Health Products For You offers a wide range of the best cream for fungal infections from leading manufacturers to protect sensitive perineal skin and maintain hygiene. Place your order today and start feeling better fast!

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Disclaimer: All content found on our website, including images, videos, infographics, and text were created solely for informational purposes. Our reviewed content should never be used for the purpose of diagnosis or treatment of any medical conditions. Content shared on our websites is not meant to be used as a substitute for advice from a certified medical professional. Reliance on the information provided on our website as a basis for patient treatment is solely at your own risk. We urge all our customers to always consult a physician or a certified medical professional before trying or using a new medical product.


HPFY HPFY Staff Writer

HPFY Staff Writer

HPFY Staff Writers are product experts with years of experience in medical supplies and equipment retail. They specialize in understanding the typical usage of our products, the differentiation between brands and have insights on product popularity and features. Each article ...

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