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The 10 Best Antifungal Creams in 2024

The 10 Best Antifungal Creams in 2024
HPFY Staff Writer

10 Best Creams for Fungal Infections

Best For

1. Medline Remedy Phytoplex Antifungal Ointment Itching & burning due to fungal infection
2. Coloplast Baza Moisture Barrier Antifungal Cream Perineal skin irritation due to fungal infection
3. Dynarex Antifungal One Percent Clotrimazole USP Cream Superficial fungal skin infections
4. Medline Soothe and Cool INZO Antifungal Cream Maintaining healthy skin while treating fungal infections
5. Dermarite Periguard Skin Protectant Antimicrobial Ointment Skin irritations associated with incontinence
6. Coloplast Critic Aid Clear AF Antifungal Moisture Barrier Perineal skin irritation due to fungal infection
7. McKesson Antifungal 2% Strength Cream Jock itch, ringworm, and athlete's foot
8. Smith & Nephew Secura Antifungal Cream Superficial fungal skin infections
9. Thera Antifungal Strength Cream Most common fungal infections
10. DermaRite DermaFungal Antifungal Ointment Superficial fungal skin infections

Our skin is our largest organ and protects us from a plethora of germs and bacteria. It regulates body temperature, preserves water, absorbs sweat, and helps create vitamin D from sun exposure. However, sometimes bacterial and fungal growth can lead to skin infections, causing irritation, rashes, swelling, inflammation, and discomfort.

An antifungal cream treats skin infections caused by microscopic single-celled organisms called fungi that may live on human skin. Fungi can cause allergies, rashes, and even acute skin infections. These fungal infections are often treated with antifungal ointments and creams.

What is an antifungal cream? 

Antifungal creams treat fungal infections of the skin, hair, and nails and are available over the counter or by prescription. Antifungal medicines come in several forms, including creams, lotions, and sprays.

When to use an anti-fungal cream

Over-the-counter antifungal cream helps treat many types of fungal infections, including:

  • Ringworm 
  • Jock itch 
  • Athlete’s foot 
  • Tinea versicolor 
  • Yeast infections 
  • Nail infections

Mild fungal skin infections are easily treatable with strong antifungal creams and ointments. However, for untreatable fungus infections, it is best to consult a dermatologist to assess and offer treatment options.

How does an antifungal cream work? 

Creams for fungal infection work by hindering the growth of the fungus or killing it altogether and repairing damaged cell walls.

Typically, topical fungal infection creams consist of various ingredients effective in treating fungus infections, such as: -  

  • clotrimazole 
  • amorolfine 
  • econazole 
  • ketoconazole 
  • miconazole 
  • terbinafine 
  • tioconazole 

Antifungal cream for the skin is often mixed with other topical creams when two skin problems are addressed together. 

Best Antifungal Creams For Itchy Or Irritated Skin

Formulated with phytoalexin and other botanicals to help relieve itching, scaling, cracking, burning, soreness, redness, irritation, and discomfort associated with the most common superficial fungal infections of the skin. It creates an invisible shield that allows easy inspection. Moreover, Medline topical antifungal cream is also ideal for children over two years to geriatrics.

Benefits of using Remedy Phytoplex Cream for Fungal Treatment

  • Miconazole nitrate 2.0% in a petrolatum base formula softens skin.
  • Helps relieve cracked, scaly, itchy, and inflamed skin.
  • This ointment is ideal for:
    • Tinea cruris - jock itch
    • Tinea corporis - ringworm
    • Tinea faciei - facial fungal infection
    • Tinea manuum - a fungal infection of the hands
    • Tinea pedis - athlete's foot
Medline Remedy Phytoplex Antifungal Ointment


Inhibits fungal growth and works great on diaper rash, ringworm and athlete's foot by locking out moisture and allowing the infection to heal without irritating the skin. Coloplast Baza is the best antifungal cream for diaper rash that offers a soothing shield against urine and feces and relieves diaper dermatitis. Additionally, zinc oxide treats burning, itching and other painful symptoms of skin infections.

Benefits of using Coloplast Baza Cream

  • Coloplast diaper cream relieves fungus infection and diaper dermatitis.   
  • Provides a moisture barrier against feces, urine, and odor.  
  • Coloplast Baza is ideal for the treatment of perineal skin irritation. 
  • The miconazole nitrate cream wicks moisture away and prevents the growth of infection-causing fungus. 
  • Eliminates itching, redness, and burning and speeds healing.
Coloplast Baza Moisture Barrier Antifungal Cream


Formulated with one percent clotrimazole, this cream works great for infections like athlete's foot, jock itch, and ringworm. Dynarex jock itch cream treats superficial skin infections caused by yeast and soothes itching, cracked, scaly, irritated skin.

Features of Dynarex Clotrimazole Antifungal Cream

  • The long-lasting non-greasy formula
  • Helps relieve pain, discomfort, and irritation
  • Treats athlete's foot, jock itch, and vaginal yeast infections.
  • Suitable for long-term care facilities and first aid kits
Dynarex Antifungal One Percent Clotrimazole USP Cream


Effectively treats athlete's foot, jock itch, ringworm, and Candida albicans, this lightly scented ointment is formulated with 2% miconazole, known for its antifungal properties. This cream provides moisture barrier protection to the affected area and protects the skin from infections caused by incontinence and ostomy.

Benefits of Medline Soothe and Cool Cream

  • The clear formula for easy monitoring of the affected area.
  • Formulated with Cetyl Dimethicone and Zinc Oxide
  • Ideal to use around ostomy sites or peri-wound skin
  • Effective on dry skin.
Medline Soothe and Cool INZO Antifungal Cream


Versatile and effective, this topical ointment promotes healing while protecting skin. Formulated with a blend of ingredients, including zinc oxide and dimethicone, which work together to create a barrier that shields the skin from moisture, irritants, and harmful bacteria. Helps to prevent and treat diaper rash, chafing, and skin breakdown caused by prolonged exposure to moisture. Also grat for minor cuts, burns, and skin irritations.

Benefits of Periguard Skin Protectant Ointment

  • Fragrance-Free skin protectant ointment
  • Treats skin irritations associated with incontinence
  • Petroleum-based skin protective cream
  • Non-greasy
  • Washes off easily
Dermarite Periguard Ointment


Highly recommended as an effective bedsore treatment, this easy-to-apply fungal infection cream heals skin and pressure ulcers by creating a barrier against moisture.

Benefits of Critic Aid Clear AF Antifungal Moisture Barrier

  • R Qelieves perineal skin irritation.
  • Provides effective treatment of jock itch.
  • Minimizes the discomfort of diaper rash.
Coloplast Critic Aid Clear AF Antifungal Moisture Barrier


Formulated with 2% miconazole nitrate to relieve jock itch, ringworm, and athlete's foot, this cream minimizes itching, cracking, and scaly skin caused by fungus infection.

The McKesson Antifungal Foot Cream Features

  • Latex-free
  • Reduces discomfort
  • Relieves redness and burning
McKesson Antifungal 2% Strength Cream



Jock itch, ringworm, and athlete's foot are some of the most common fungal infections. Smith & Nephew antifungal cream helps relieve itching and irritation caused by fungal growth. It contains zinc oxide to protect the skin from exposure to urine and feces, and the thick formula soothes the scaling and chaffing skin.

Features of Smith & Nephew Secura Antifungal Cream 

  • Absorbs quickly into the skin
  • Clinically tested for pediatric use
  • Non greasy formula soothes burning and irritation
  • It contains karaya to control moisture and vitamin E for skin conditioning
Smith & Nephew Secura Dimethicone Skin Protectant Cream


Formulated with 2% Miconazole Nitrate to help fight most superficial fungal skin irritations and yeast infections. This moisturizing cream relieves itchy, cracked, scaly, burning, red skin.


Benefits of Thera Antifungal Strength Cream

  • Helps protect against excess moisture in skin folds and inflamed areas.
  • Moisturizes the skin where incontinence or wound drainage is an issue
  • Recommended for skin folds and feet.
  • Latex-free
Thera Antifungal Strength Cream



Dermarite can treat common fungal infections and protects against candida infections, the main culprits behind diaper rash or vaginal yeast infections. It is applied directly on the skin and works fast.

Features of Dermarite Dermafungal Cream

  • It contains 2% Miconazole Nitrate to inhibit fungal growth.
  • Absorb quickly into the skin
  • Works for all skin types
  • Suitable for adults and children (over the age of two)
Buy DermaRite DermaFungal Antifungal Ointment



Where can I buy Best Antifungal Cream Over The Counter?

Health Products For You offers a wide range of the best cream for fungal infections from leading manufacturers to protect sensitive perineal skin and maintain hygiene. Place your order today and start feeling better fast!

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Disclaimer: All content found on our website, including images, videos, infographics, and text were created solely for informational purposes. Our reviewed content should never be used for the purpose of diagnosis or treatment of any medical conditions. Content shared on our websites is not meant to be used as a substitute for advice from a certified medical professional. Reliance on the information provided on our website as a basis for patient treatment is solely at your own risk. We urge all our customers to always consult a physician or a certified medical professional before trying or using a new medical product.


HPFY HPFY Staff Writer

HPFY Staff Writer

HPFY Staff Writers are product experts with years of experience in medical supplies and equipment retail. They specialize in understanding the typical usage of our products, the differentiation between brands and have insights on product popularity and features. Each article ...

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