Systagenix Promogran Prisma Matrix Wound Dressing

Brand/Manufacturer: ACELITY/SYSTAGENIX
Item # Desc Pkg Price
MA028 4.34 sq. in. $0.80
MA032 Rope, 3/8" x 3/8" x 12-5/8" $3.43
MA032 Rope, 3/8" x 3/8" x 12-5/8" $20.50
MA028 4.34 sq. in. $7.78
MA028 4.34 sq. in. $30.00
MA123 19.1 sq. in. $2.02
MA123 19.1 sq. in. $19.50
MA123 19.1 sq. in. $72.93

Promogran Prisma Matrix Wound Dressing is used for the management of exuding wounds. It is designed to kick start the healing process while providing protection from infection. Prisma Wound Dressing absorbs destructive components of chronic wound fluid and creates the optimal environment for cellular development. It is a simple-to-use primary dressing.

Why choose Promogran Prisma Matrix Wound Dressing?

  • Systagenix Promogran may be used under compression therapy with healthcare professional supervision
  • Presence of silver prevents anti-microbial activity in the wound bed promoting quicker healing time
  • This Promogran Prisma Matrix collagen wound dressing can be pre-moistened to form a gel and molded to fit the wound, or it can be cut with sterile scissors to fit the wound shape
  • Prisma dressing for wounds has known haemostatic properties
  • Not necessary to remove any Promogran Prisma residue from the wound
  • Ideal for all the areas of the body
  • Can be worn for up to seven days depending on wound conditions
  • Shape: Hexagon
  • Sterile

What is Prisma Wound Dressing used for?

Under the supervision of a healthcare professional, Promogran Dressing can be used for the management of:
  • Diabetic Ulcers
  • Venous ulcers
  • Pressure ulcers
  • Ulcers caused by mixed vascular etiologies
  • Full-thickness and partial thickness wounds
  • Donor sites and other bleeding surface wounds
  • Abrasions
  • Traumatic wounds healing by secondary intention
  • Dehisced surgical wounds

How does Promogran Prisma For Wounds Dressing work?

Promogran Prisma Wound Dressing is a sterile, freeze dried, composite of collagen, silver-ORC and oxidized regenerated cellulose (ORC).

Optimum Wound Environment

Promogran Prisma Matrix transforms into a soft, conformable, biodegradable gel in the presence of exudate, allowing contact with all areas of the wound. A moist micro-environment is maintained at the wound surface, which is conducive to epithelialization, granulation tissue formation, and optimal wound healing.

Role Of Silver in Promogran Prisma Matrix

Silver-ORC is said to be comprised of 25% w/w ionically bound silver, which is a well-known antimicrobial agent. Systagenix Prisma dressing with silver provides an effective antimicrobial barrier that helps in reduction of bacterial development with common wound pathogens such as, Pseudomonas aeruginosa, Staphylococcus aureus, Eschericia coli, and Streptococcus pyogenes. Reduction of bacterial bioburden in the dressing may result in reduced risk of infection.

What is ORC?

Cellulose is a major component of all plants. Once oxidized, ORC (Oxidized Regenerated Cellulose) is completely bioresorbable, and readily degrades through fluid absorption and subsequent gelling.
Tissue Repair
Tissue Repair
Cell Growth
Cell Development
Control Bacterial Growth
Control Bacteria Development

Promogran Prisma User Guide

What to buy with Promogran Wound Dressing?

How to use Prisma Matrix Wound Collagen Dressing?

  • Before application, necrotic tissue must first be removed by debridement.
  • For optimal effect, apply Prisma Matrix Wound Dressing directly to the whole wound bed.
  • For a wound with low or no exudate apply Prisma Wound Dressing and hydrate with saline solution. This will initiate the transformation of the Promogran Prisma Matrix into a gel.
  • After hydration, the Promogran Prisma gel will come in contact with the wound surface. The biodegradable Promogran Prisma Matrix gel is naturally absorbed into the body over time.
  • In order to maintain a moist wound healing environment Promogran Prisma Dressing must be covered with a semi-occlusive dressing (e.g. Bioclusive Transparent Dressing, Tielle or Tielle Plus Hydropolymer Dressings) or a non-occlusive secondary dressing and fixed to the skin with a non-irritating tape.
  • After initial application, re-apply Prisma Collagen Dressing to the wound daily as per physician recommendation.
  • It is not necessary to remove any residual of Prisma Dressing during dressing changes.

Prisma Matrix Storage Instructions

  • Promogran Prisma Matrix Wound Dressing should be stored away from direct light.
  • Over-exposure to light may cause some discoloration, however this does not affect the release of silver from the dressing.
  • Store below 25 degrees C / 77 degrees F.

Precautions to take while using Prisma Matrix Wound Dressing

  • Only when proper medical treatment addresses the underlying cause, the Promogran Prisma Dressing may be used when visible signs of infection are present in the wound.
  • Not intended to be a substitute for appropriate treatment of infection.
  • Healthcare professionals/clinicians should be aware of the fact that there is very limited data available on prolonged and repeated use of silver containing dressings, particularly in children and neonates.

What does Promogran Prisma Matrix Dressing contain?

  • 44% oxidized regenerated cellulose (ORC)
  • 55% collagen
  • 1% silver-ORC, which contains 25% w/w ionically bound silver


  • Patients with known sensitivity to silver, ORC or collagen
  • Third-degree burns

Prisma Matrix Dressing Reviews


ItemName - now     10/19/2021

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UserName - now     10/19/2021

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Karla     09/20/2015

can it be used in conjunction w/ a wound vac?


Customer Service    09/22/2015

Thank you for reaching out to us. 

I have spoke with KCI (formerly Systagenix Wound Management) who is the manufacturer of the product. The product you mentioned is NOT recommended for use with Vac Therapy (WoundVac).

Per the clinical nurse, the product becomes gelatinous when moist and therefore can be sucked through the tubing of the Vac limiting its effectiveness if not causing a malfunction altogether. They do not have any dressings specifically recommended for the proposed use. 

Feel free to contact them directly at 1-800-275-4524 ext 56650.



Sharon     04/12/2015

How often should dressing be changed?


Customer Care    04/13/2015

Thank you for reaching out to us. The interval between dressing changes is determined principally by the condition of the wound. In heavily exuding wounds, it may be necessary to replace the matrix daily initially, but on lightly exuding wounds it may be left undisturbed for 2 to 3 days.



Jim     10/07/2014

When is treatment contraindicated?


Customer Care    12/27/2014

Neither product should be used on patients with full-thickness burn injuries, active vasculitis or a known hypersensitivity to either collagen or ORC. If infection is present or suspected, it should be treated according to local policy. Promogran Prisma can be used with systemic antibiotics to treat infection.



Jessica     10/06/2014

When should treatment be discontinued?


Customer Care    10/07/2014

There is no need to stop Promogran Prisma if the wound is progressing well. However, if the wound is epithelialising and there is no exudate, it may be more appropriate to change to a simple non-adherent dressing.



Billie     10/02/2014

What factors indicate this is the right dressing choice?


Customer Care    10/03/2014

During the first few dressing changes there should be a change in the colour of the wound bed and a reduction in the amount of sloughy tissue present. Following two weeks of treatment there should be a marked reduction in the level of exudate. Often the first change is that patients report a reduction in the level of pain experienced.



Iracema     09/29/2014

Can it be used under compression bandage?


Customer Care    10/01/2014

It can be used under compression bandaging and does not cause indentation, skin irritation or maceration, even when the dressing is overlapped at the wound edge.



Henry     09/19/2014

What is the frequency of change?


Customer Care    09/20/2014

  • Based on instructions of use, the dressing should be changed every 72 hours or more frequently if the exudate level is high.
  • If the gel has not biodegraded the dressing should be left in place until the next dressing change, minimising disturbance to the wound.
  • If there is no residue of gel in the wound bed or traces left on the secondary dressing and the wound bed is clean and granulating, the dressing has fully biodegraded.



David     09/13/2014

How do I use it?


Customer Care    09/15/2014

  • Prepare the wound bed - removal of necrotic or sloughy tissue and any previous dressings.
  • Assess the level of exudates - a small amount of saline can be added to the surface of the dressing once it has been applied to the wound bed. This helps to initiate the breakdown of the dressing and its ability to modify the wound environment.
  • Apply the dressing - Place the dressing in the wound bed. If the patient has multiple small wounds the dressing can be broken into smaller pieces with a gloved hand.
  • Dressing review – Based on instructions of use, the dressing should be changed every 72 hours or more frequently if the exudate level is high.



Kathleen     09/05/2014

When do I use Promogran Prisma?


Customer Care    09/06/2014

PROMOGRAN PRISMA Matrix is indicated for the management of all wounds healing by secondary intent which are clear of necrotic tissue including:

  • Diabetic ulcers
  • Venous ulcers
  • Pressure ulcers
  • Ulcers caused by mixed vascular aetiologies
  • Traumatic wounds and surgical wounds It has known haemostatic properties and can be used under compression therapy.



Anna     08/13/2014

What is the role of collagen in tissue repair?


Customer Care    08/14/2014

  • Helps to stop bleeding (haemostatic properties)
  • Has a low-inflammatory and low-antigenic response, which does not cause an adverse reaction (even when collagen from different species is used)
  • Enhances the deposition of new collagen and reduces wound contraction
  • Collagen fragments (peptides – formed on degradation of the dressing) can attract cells into the wound area (chemotaxis) and induce cell growth (cell proliferation)
  • Collagen peptides break down to amino acids, which can be reused by the cells to help build new proteins
  • Reduces MMP activity, an effect that helps control the proteolytic environment in the chronic wound


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What is HPFY’s return policy?

Customer satisfaction is our top priority. We stand behind our products. If the merchandise you received is defective or not what you expected it to be, and you wish to return the item, please submit a return request in the My Account section of our website, contact our Customer Service department at (866) 316-0162 / (203) 616-2850 or email us.

  1. Merchandise must be returned within 30 days of the receipt of your order. Returns are not accepted after 30 days.
  2. Items (including parts and accessories) must be returned in new, unused, and resalable condition in its original packaging.
  3. Before returning any product, the buyer must obtain a Return Authorization Number (RA#) from a customer service representative. With your RA# you will receive a prepaid return shipping label.
  4. Orders returned without obtaining an RA# will be entitled to receive only "In-Store Credit" that can be used towards future purchases.
  5. Return orders are subject to a 20% restocking fees.
  6. All custom orders and hygienic items are non-returnable. Refer to the “Non-Returnable Items” section for further details.
  7. Returns will be reviewed and inspected before issuing credit. Please allow 3 to 4 weeks for processing. The credit will be applied to your original method of payment.
  8. If the return is the result of a defective product or shipping error, we will refund the entire purchase amount and return shipping costs.

Which products are Non-Returnable?

Due to the hygienic nature of some items, they are non-returnable. The items listed below are non-returnable:

  1. All hygienic items.
  2. Opened personal care items.
  3. Anything opened, used, or tried on.
  4. All customized items.
  5. Besides these, items that have the “non-returnable” phrase on the website.

We reserve the right to make adjustments due to errors, changing market conditions, product discontinuation or typographical errors in advertisements. Images on the site may not always reflect the actual product. Footrests or leg-rests are not included with wheelchairs unless specified.

How do I receive a return authorization number?

You can submit a return request by logging into your account. You will receive the Return Authorization Number (RA#) details in the email within 2-3 business days.

  • Login to your account
  • Go to “order history”
  • Click on “return order”
  • Fill out the return form and Submit it

If you do not have an email address, we will make other accommodations for RA# Details. Write the RA# on your label affixed to your package prior to shipment.

How long does it take to receive a refund?

Please allow 3 to 4 weeks to process the returns. Once the item is received, and inspected, your refund will be processed and automatically applied to your credit card or original method of payment.

Is there any Restocking Fees?

  1. 20% restocking fees will be applied.
  2. Outbound shipping cost is non-refundable.
  3. For orders that qualified for free shipping, $8.99 will be deducted from the refund if the product is returned.

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