Systagenix Promogran Matrix Wound Dressing

Brand/Manufacturer: ACELITY/SYSTAGENIX
Item # Desc Pkg Price
PG004 4.34 sq. in. Hexagon $0.65
PG004 4.34 sq. in. Hexagon $6.40
PG004 4.34 sq. in. Hexagon $24.50
PG019 19.1 sq. in. Hexagon $1.82
PG019 19.1 sq. in. Hexagon $17.00
PG019 19.1 sq. in. Hexagon $64.15

Systagenix Promogran Matrix Wound Dressing is comprised of a freeze-dried composite of 55% collagen and 45% oxidized regenerated cellulose (ORC). It maintains a physiologically moist microenvironment at the wound surface that helps optimize and promote healing. This environment is conducive to granulation tissue formation, epithelization and rapid healing of the wound. In the presence of exudate, Promogran Matrix Dressing transforms into a soft, conformable and biodegradable gel. This allows contact with all the areas of the wound. Promogran Matrix is clinically proven to heal chronic wounds faster.

Why choose Promogran Dressings?

  • Can be cut with sterile scissors
  • haemostatic properties
  • Sterile
  • Versatile
  • Hexagon shape

Promogran Matrix Wound Dressing Features

  • Primary wound dressing, which is easy to use and appropriate for multiple wound types
  • May be used under compression therapy with supervision of a healthcare professional
  • Can be cut with sterile scissors to fit any wound shape or it can be pre-moistened to form a gel and molded to fit the wound
  • Promogran matrix has demonstrated haemostatic properties
  • Not necessary to remove any residual Promogran Matrix at dressing changes as it will be naturally absorbed into the body over time
  • Retreat the wound with Promogran Matrix up to every 72 hours depending on the amount of exudate
  • Efficacy of Promogran Dressing is supported by clinical evidence, including 11 published RCTs

When to use Promogran Collagen Dressing?

Systagenix Promogran Matrix Dressing is intended for the management of exuding wounds including:
  • Diabetic ulcers
  • Venous ulcers
  • Ulcers caused by mixed vascular aetiologies
  • Abrasions
  • Pressure ulcers
  • Donor sites and other bleeding surface wounds
  • Full-thickness and partial thickness wounds
  • Dehisced surgical wounds
  • Traumatic wounds healing by secondary intention

How does Promogran Matrix Work?

When applied to a wound, collagen/ORC binds to proteases and inactivates them, reducing their levels of activity such as matrix metalloproteinases (MMPs) and elastase. This may restore balance to the microenvironment of the wound, promoting granulation tissue and helping the wound to close. Wounds with elevated protease activity (EPA), assessed using Woundchek Protease Status point, have a 90% probability that they will not heal without appropriate intervention. EPA can be identified using the Woundchek Protease Status test. When protease and elastase activity are reduced, a wound is more likely to heal. Collagen/ORC also has the ability to reduce the wound surface area. Collagen alone has been shown to be less effective in reducing the protease activity than the combination of collagen and ORC.

How Promogran Matrix Work

What to buy with Systagenix Promogran Wound Dressing

How to use Promogran Matrix Wound Dressing?

How To Use Promogran MatrixPreparation
  • Prepare the wound as per standard wound care protocol and debride when necessary
  • Peel back the tray cover and leave dressing in tray
  • If necessary, Promogran can be cut using clean scissors or folded to fit the wound bed
How To Use Promogran MatrixApplication
  • Apply directly to wound, covering the entire wound bed
  • For small, deep or wet wound, cut the dressing prior to application or pack dressing into the wound
  • If the wound is dry, moisten the dressing in the wound or in the tray
How To Use Promogran MatrixSecondary Dressing Application
  • Cover with a non-adherent contact layer such as Adaptic Touch or a foam dressing such as Tielle
  • Choose the secondary dressing based on the level of exudate
  • Apply any cover or retention/compression bandage if required

Significance Of Collagen/ORC in Promogran Dressing

Promogran is collagen (55%)/ORC (45%) containing matrix, for use where the wound is not at particular risk of increased bioburden, nor showing signs of increased bioburden. These are both natural materials that are readily broken down or reabsorbed when placed in the wound. When the collagen/ORC matrix comes into contact with fluid/ exudate in the wound, it absorbs the liquid to form a soft gel. This allows the Collagen Dressing to conform to the shape of the wound and come into contact with all areas of the wound. The gel physically binds to and inactivates damaging proteases, both matrix metalloproteases (MMPs) and elastase that are present within the wound. In addition, it binds with naturally occurring growth factors and prevents them from being broken down by damaging proteases. As the matrix slowly breaks down, the growth factors are released back into the wound in an active form, while the damaging proteases remain inactive.

Important Tips while using Promogran Collagen Dressing

  • Before treatment, dry necrotic tissue must first be removed by surgical, enzymatic or autolytic debridement.
  • For optimal effect, apply matrix directly to the entire wound bed.
  • For a wound with low or no exudate apply matrix and hydrate with saline or Ringer solution. Alternatively, the matrix can be pre-wetted with saline or Ringer solution before application using the tray it is pre-packaged in.
  • The matrix can be cut or folded and packed into deeper wounds.
  • The matrix must be covered with either gauze, a non-adhering or a hydro polymer dressing and can be used along with appropriate compression therapy or offloading.
  • After hydration the matrix forms a gel. This biodegradable gel is naturally absorbed over time.
  • It is not necessary to remove any residual matrix/gel. Reapply the matrix up to every 72 hours depending on the volume of exudate.

  • Patients with known hypersensitivity to the components of this product, i.e. ORC and collagen
  • Full-thickness burn injuries and active vasculitis
  • Discontinue use if signs of sensitivity appear
  • If infection is suspected during treatment, an appropriate antimicrobial dressing or systemic therapy should be used

Promogran Matrix Wound Dressing Reviews


ItemName - now     09/20/2021

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UserName - now     09/20/2021

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Lisa Hough     07/27/2020

What is the difference between the matrix or prisma?


Customer Care    10/28/2020

  • Systagenix Promogran Matrix Wound Dressing is comprised of a freeze-dried composite of 55% collagen and 45% oxidized regenerated cellulose (ORC). It maintains a physiologically moist microenvironment at the wound surface that helps optimize and promote healing.
  • Promogran Prisma Matrix Wound Dressing is used for the management of exuding wounds. It is designed to kick start the healing process while providing protection from infection. Prisma Wound Dressing absorbs destructive components of chronic wound fluid and creates the optimal environment for cellular growth. It is a simple-to-use primary dressing.



Lucy     03/15/2017

When is the treatment contraindicated?


Customer Care    03/15/2017

Promogran Matrix should not be used on patients with full-thickness burn injuries, active vasculitis or a known hypersensitivity to either collagen or ORC. If infection is present or suspected, it should be treated according to local policy.



Catherine     03/15/2017

What factors indicate that this is the right dressing choice?


Customer Care    03/15/2017

During the first few dressing changes there should be a change in the colour of the wound bed and a reduction in the amount of sloughy tissue present. Following two weeks of treatment there should be a marked reduction in the level of exudate. Often the first change is that patients report a reduction in the level of pain experienced.



Plasy     03/15/2017

When should treatment be discontinued?


Customer Care    03/15/2017

There is no need to stop Promogran Matrix if the wound is progressing well. However, if the wound is epithelialising and there is no exudate, it may be more appropriate to change to a simple non-adherent dressing.



Nancy     02/07/2017

What is the HCPC for Promogran dressings?


Customer Care    02/08/2017

The HCPCS codes for Promogran Matrix Wound Dressings are:

Code PG004     HCPCS Code: A6021 
Code PG019     HCPCS Co de:A6022


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What is HPFY’s return policy?

Customer satisfaction is our top priority. We stand behind our products. If the merchandise you received is defective or not what you expected it to be, and you wish to return the item, please submit a return request in the My Account section of our website, contact our Customer Service department at (866) 316-0162 / (203) 616-2850 or email us.

  1. Merchandise must be returned within 30 days of the receipt of your order. Returns are not accepted after 30 days.
  2. Items (including parts and accessories) must be returned in new, unused, and resalable condition in its original packaging.
  3. Before returning any product, the buyer must obtain a Return Authorization Number (RA#) from a customer service representative. With your RA# you will receive a prepaid return shipping label.
  4. Orders returned without obtaining an RA# will be entitled to receive only "In-Store Credit" that can be used towards future purchases.
  5. Return orders are subject to a 20% restocking fees.
  6. All custom orders and hygienic items are non-returnable. Refer to the “Non-Returnable Items” section for further details.
  7. Returns will be reviewed and inspected before issuing credit. Please allow 3 to 4 weeks for processing. The credit will be applied to your original method of payment.
  8. If the return is the result of a defective product or shipping error, we will refund the entire purchase amount and return shipping costs.

Which products are Non-Returnable?

Due to the hygienic nature of some items, they are non-returnable. The items listed below are non-returnable:

  1. All hygienic items.
  2. Opened personal care items.
  3. Anything opened, used, or tried on.
  4. All customized items.
  5. Besides these, items that have the “non-returnable” phrase on the website.

We reserve the right to make adjustments due to errors, changing market conditions, product discontinuation or typographical errors in advertisements. Images on the site may not always reflect the actual product. Footrests or leg-rests are not included with wheelchairs unless specified.

How do I receive a return authorization number?

You can submit a return request by logging into your account. You will receive the Return Authorization Number (RA#) details in the email within 2-3 business days.

  • Login to your account
  • Go to “order history”
  • Click on “return order”
  • Fill out the return form and Submit it

If you do not have an email address, we will make other accommodations for RA# Details. Write the RA# on your label affixed to your package prior to shipment.

How long does it take to receive a refund?

Please allow 3 to 4 weeks to process the returns. Once the item is received, and inspected, your refund will be processed and automatically applied to your credit card or original method of payment.

Is there any Restocking Fees?

  1. 20% restocking fees will be applied.
  2. Outbound shipping cost is non-refundable.
  3. For orders that qualified for free shipping, $8.99 will be deducted from the refund if the product is returned.

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