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Silvadene - Silver Sulfadiazine Cream For Burns

Brand: PFIZER INC SKU: 61570-131-98

Note: Item 61570-131-40, 61570-131-98 is on backorder and will be shipped once it is back in stock.

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100gm Silvadene Cream

SKU 61570-131-98
$344.08 Each
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Silvadene Topical Burn Cream (silver sulfadiazine) is a topical antimicrobial agent applied directly to the wound site, most commonly to second-degree and third-degree burns. The burns should always remain covered with the cream to eliminate and reduce infection risks. Patients are advised to continue using the cream until the area has healed to an adequate level or until the wound is ready for skin grafting.

Silver Sulfadiazine Cream For Burns is a soft, white, water-miscible cream containing the antimicrobial agent silver sulfadiazine in micronized form, which has the following structural formula:

Chemical formula of Silvadene

Ingredients of Silvadene Cream

Each gram of Silvadene Cream 1% contains -

  • 10 mg of micronized silver sulfadiazine
  • White petrolatum
  • Stearyl alcohol
  • Isopropyl myristate
  • Sorbitan monooleate
  • Polyoxyl 40 stearate
  • Propylene glycol
  • Water
  • Methylparaben 0.3% as a preservative


$319.08 $533.39

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5% Off* on future orders

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One-time purchase

$344.08 $533.39

Earn $17.20 in HPFY rewards

Why Choose Silvadene Cream?

  • Silvadene contains antimicrobial properties of the sulfa drug class
  • It kills harmful microorganisms by attacking their cell membrane and their cell walls
  • This Burn care cream also suppresses the growth of bacteria and yeast-like Candida Albicans
  • Studies find Silvadene Cream to be better than Ag- PHEMA, Sulfamylon, or cerium-Silvadene.
  • Silvadene Ointment can be applied and left open or covered by a dressing, as per requirements.

What is Silver Sulfadiazine Cream used for?

Indications of Silvadene Burn Cream

  • Second Degree Burns
  • Third Degree Burns
  • Severe Sunburns

Contraindications of Micronized Silver Sulfadiazine

  • Allergic reaction and sensitivity to silver or any ingredients
  • Pregnancy
  • Premature infants
  • Infants below 2 months of age

Side Effects of Silvadene Burn Cream

  • Fatigue or weakness
  • Sore throat
  • Pain in joints
  • Yellowing of the eyes or skin
  • Transient leukopenia (decreased neutrophil count)
  • Skin necrosis
  • Erythema multiforme
  • Skin discoloration
  • Burning sensation
  • Rashes,
  • Interstitial nephritis
  • Unexplained bruising or unusual bleeding
  • Blood in urine

If any of the above symptoms are visible in the patient, immediately contact the family doctor and stop using the cream until further clearance.

How to Apply Silver Sulfadiazine Cream for Burns?

Cleaning the wound
1. Clean the wound site, and remove any debris or dead and burnt skin

Wear Medical Gloves
2. Wear gloves if applying by hand

Apply Silvadene Silver Sulfadiazine Cream
3. Apply a thin layer of cream covering the wound and perineal area

Apply Bandage
4. Cover the wound or keep it open as advised

Reapply when cream wears off
5. Reapply the ointment once it wears off every few hours


Administered Dosage of Silvadene Cream for Burns

  • Grown-ups are required to apply Silvadene twice a day and reapply when it wears off from daily tasks.
  • It is advised to consult a physician for the dosage requirements of a child
  • Users are recommended to continue the use of Silvadene until the wound has healed or the site is ready for skin grafting.

Silvadene Silver Sulfadiazine Cream - FAQs

  • How long should you use Silvadene on a burn?

    Silver Sulfadiazine Cream should be used throughout the day until the wound heals or the skin is ready for grafting.

  • How many times a day should you use Silvadene?

    Silvadene Cream should be applied twice a day in 10-12 hr. cycles and reapplied if it wears off in day-to-day tasks.

  • How long does it take for silver sulfadiazine to work?

    A study reveals that wound healing among users of SSD (Silver Sulfadiazine) was evident in 72% of patients by day 7, and 84% were completely healed by day 21.

  • Can you put Silvadene on an open wound?

    Yes, for most surface wounds applying Silvadene on an open wound after debriding will prevent infection and keep bacteria at bay.

  • What does Silvadene do for a burn?

    The Silver Sulfadiazine present in Silvadene Cream helps kill bacteria and prevent infection from spreading in the bloodstream that may cause severe issues like Sepsis.

  • Does Silvadene cream help with pain?

    Application of Silvadene Burn Cream Silver on severe sunburns reported decreased pain and faster healing.

  • Does Silvadene turn skin black?

    No. The cream does turn black as the silver ion oxidizes, but the black pigments are not incorporated into the skin. The permanent discoloration is due to the burn and may eventually fade away.

  • Does Silvadene lower your White Blood Cell count?

    There is a small risk of having a lower white blood cell count (leukopenia) when you use Silvadene. Low white blood cell count usually happens two to four days after a person starts treatment with Silvadene.

Silvadene Burn Cream Reviews


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